NPLEX II Pharmacology Practice Test

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• Which substance is described as a naturally occurring estrogen?
• Which opioid antagonist is used to treat opioid dependence and alcohol dependence?
• Which drug is a Schedule II narcotic analgesic with contraindications including paralytic ileus, lactation, and age under 18?
• Which drug is an anesthetic used for introduction of local anesthesia of accessible mucous membranes and is Schedule II?
• Which medication is contraindicated in pregnancy due to teratogenic risk?
• The polio vaccine provides which protection?
• Which medication is contraindicated during lactation?
• Naloxone is best described as which type of drug?
• Conjugated estrogens are used for which of the following indications?
• Before 1985, MDMA was studied for use in which therapeutic setting?
• Cyproheptadine is an antihistamine and, in some countries, is used as what?
• What is the pregnancy category for loperamide?
• Which antianginal drug has a contraindication with sildenafil due to potential serious interactions?
• Which vaccine combines meningococcal A, C, Y, and W-135 polysaccharides?
• Hydrochlorothiazide is a thiazide diuretic that is contraindicated in patients with allergy to which class?
• Androstenedione is a direct precursor to which hormone?
• Alendronate is best classified as which of the following?
• Which drug is a calcineurin inhibitor used to prevent organ transplant rejection?
• Which statement about atorvastatin is true?
• Which opioid is commonly prescribed in combination with acetaminophen for pain relief?
• Which vaccine is a live, attenuated vaccine?
• Which vaccine provides active immunization against measles, mumps and rubella?
• Which atypical antipsychotic is used for schizophrenia and other psychotic disorders and has lactation contraindication?
• Which drug is an opioid receptor antagonist used to reverse opioid effects?
• Which medication is an NMDA receptor antagonist used as an anesthetic adjunct?
• What is the pregnancy category for salmeterol?
• Which BPH medication is contraindicated during lactation?
• Vinblastine is used to treat which conditions?
• Prochlorperazine carries a boxed warning for which population?
• Which agent is a uterine stimulant used for postpartum hemorrhage, induction of labor, and incomplete abortion?
• Pseudoephedrine acts as which type of agent and what is a noted side effect?
• Which skeletal muscle relaxant is used for painful muscle spasms and has pregnancy category B?
• Which drug is primarily an anticholinergic used to treat bradycardia and organophosphorus poisoning?
• DMPS chelates metals; which metal is NOT among its targets?
• Trimethoprim-sulfamethoxazole is commonly used for which conditions?
• Phenylephrine is a decongestant and may cause which ocular effect when used as eyedrops?
• Influenza vaccine provides active immunization against which of the following?
• Which agent carries a pregnancy category X?
• Which drug inhibits gastric acid secretion and is used for GERD, peptic ulcer disease, H. pylori eradication, and NSAID-associated GI bleed prevention?
• Which agent is a thiazolidinedione used in type 2 diabetes and can be used with metformin?
• Which drug is a vascular headache suppressant commonly used for migraines?
• Nitroglycerin therapy requires which of the following intervals?
• Which MAOI is used particularly for atypical depression?
• Valsartan is best described as which of the following?
• Which antibiotic carries a higher risk of Clostridium difficile pseudomembranous colitis?
• Amoxicillin is a broad-spectrum beta-lactam antibiotic used for infections at which sites?
• Which drug is a skeletal muscle relaxant indicated for painful muscle spasms in musculoskeletal conditions and has lactation contraindication?
• Which agent is used as a progestin component in contraception regimens that include estrogen?
• Zidovudine's pregnancy safety category is which?
• Loratadine is which type of antihistamine?
• Gemfibrozil is best described as which drug class?
• Which anti-Parkinson drug is given as levodopa-carbidopa and should not be given with vitamin B6 because it reverses levodopa's effects, and is contraindicated in lactation?
• Tolterodine commonly causes which anticholinergic side effect?
• Which agent has the side effect of increased brown iris pigmentation?
• Which benzodiazepine is commonly used for short-term management of anxiety?
• 5-Fluorouracil is used topically for the treatment of which condition?
• Docusate: which statement is true?
• Bromocriptine is classified pharmacologically as a
• Raloxifene is classified as which type of pharmacologic agent?
• Terbinafine is an antifungal agent belonging to which class?
• Which mood stabilizer is used for bipolar affective disorder and requires monitoring for severe toxicity above 2.5 mEq/L?
• A notable adverse effect of nitrofurantoin is which of the following?
• Deferoxamine is best described as which type of agent?
• Which medication can cause malabsorption of vitamin B12?
• Which drug carries a risk of Reye's syndrome in children under 12?
• Cyclosporine is best described as which type of drug?
• Which statement best describes mometasone in clinical use?
• Permethrin cream is used to treat which infestation?
• Which statement best describes adalimumab?
• Which anticonvulsant has Pregnancy Category D and is used for seizures, trigeminal neuralgia, bipolar prophylaxis?
• Propranolol is best described as which pharmacologic action?
• Hydroxyzine has which pregnancy category in the first trimester?
• Norgestimate is used for which purpose?
• In pregnancy, nitrofurantoin is contraindicated during which period?
• Which benzodiazepine is long-acting and indicated for severe anxiety, insomnia associated with anxiety, muscle spasms, alcohol withdrawal symptoms, and seizures?
• Prednisone is best described as which type of drug?
• Which medication has a pregnancy category B status according to the source material?
• Digoxin is most associated with which classic adverse effect?
• Which drug functions as a bronchodilator, mydriatic, and is used for anaphylactic shock when given IV or IM?
• In pharmacotherapy, nicotine is used as what agent?
• Which antidepressant also has anxiolytic properties and is used for depression, panic, and anxiety?
• Which antiulcer agent forms an ulcer-adherent barrier and is used for duodenal ulcers and stress ulcers?
• HPV Quadrivalent vaccine covers which HPV types?
• Which populations should avoid doxycycline?
• Which medication is a decongestant that can cause mydriasis when used as an eye drop?
• Which medication is described as antidepressant, smoking cessation aid, and serotonin antagonist & reuptake inhibitor (SARI)?
• Which drug is an antiplatelet used for prophylaxis of myocardial infarction and is associated with Reye's syndrome in children?
• The tuberculin purified protein derivative is used for what diagnostic test?
• Fluconazole is a systemic antifungal indicated for which of the following conditions?
• Oseltamivir is active against which influenza strains?
• Adefovir is used to treat which infection?
• Diphenhydramine is used for which of the following actions?
• 5-Fluorouracil is best described as which class of anticancer agent?
• Adalimumab is which type of biologic agent?
• Medroxyprogesterone is described as which type of hormone and what is it used for?
• Mebendazole is contraindicated in which group?
• Hepatitis A vaccine provides active immunization against which infection?
• Salmeterol is best described as which type of bronchodilator?
• Bismuth subsalicylate adverse effect: what is a notable side effect?
• Valacyclovir is primarily used as which type of medication?
• Raloxifene belongs to which class of drug?
• Which drug is a skeletal muscle relaxant with autonomic nervous system activity used for painful spasms?
• During diabetes management, which medication has a warning that its hypoglycemia signs can be masked by beta blockers?
• Which vaccine in the list is used for immunization against diphtheria and tetanus?
• Ciprofloxacin is a fluoroquinolone effective for which types of infections?
• Vinblastine is best described as which class of anticancer drug?
• Which Schedule I substance is described as having analgesic, antiemetic, appetite stimulant, and glaucoma indications?
• Which anti-ulcer agent is an H2 receptor antagonist used for peptic ulcer disease, dyspepsia, stress ulcer prophylaxis, and GERD?
• Paclitaxel is used to treat which of the following cancers?
• Warfarin is an anticoagulant used for the treatment and prophylaxis of venous thromboembolism. What is its pregnancy category?
• Rotavirus vaccine is characterized as which type of vaccine?
• Metronidazole is contraindicated in which trimester of pregnancy?
• Which drug is primarily used as maintenance therapy in COPD due to its antimuscarinic action?
• Which sedative/hypnotic is a nonbarbiturate with rapid onset and short duration of hypnotic action used for short-term management of insomnia?
• Carvedilol is best described as which pharmacologic action?
• Fluconazole carries which pregnancy category?
• Which drug is described as safe in pregnancy in the provided material?
• Estrone is described as which type of estrogen?
• Which decongestant can cause mydriasis and iris pigment changes when used as an ophthalmic solution?
• Which drug is contraindicated in lactation?
• Azithromycin is a macrolide used for which of the following infection patterns?
• Pregnenolone is described as which of the following?
• Which statement about amlodipine is true?
• Which drug acts as a toxicology antidote and is used for opioid dependence and adjunct in alcohol dependence?
• Epoetin alfa is best described as which type of agent?
• Which analgesic is used for analgesia and opioid detoxification adjunct?
• Mupirocin is best described as a
• Anastrozole is best described as which type of agent?
• Metoclopramide is a dopamine antagonist used for which condition(s)?
• Which antiglaucoma agent is associated with ocular hypertension and open-angle glaucoma and can cause increased iris pigmentation?
• Which drug is contraindicated in pregnancy due to teratogenic risk and is used for abortion induction?
• Which anxiolytic is a non-benzodiazepine and does not impair alertness, used for short-term management of anxiety?
• Tolterodine is contraindicated in which condition?
• Methyl salicylate is best described as which type of topical agent?
• Which are contraindications to TMP-SMX?
• Haemophilus influenzae type b vaccine immunizes against which infection?
• Which drug is an anesthetic adjunct and NMDA receptor antagonist used in anesthesia and is also known as a date rape drug?
• Which is a common adverse effect of furosemide?
• Which substance is a CNS stimulant and xanthine commonly used in the context of migraines?
• Which agent is an antitussive suitable for suppressing cough?
• Which medication is a natural thyroid hormone replacement used for hypothyroidism?
• Acyclovir works by which mechanism?
• Methylphenidate is best described as which of the following?
• Which drug is a nonamphetamine CNS stimulant used to improve wakefulness in patients with excessive daytime sleepiness associated with narcolepsy?
• Clindamycin is indicated for infections caused by which organisms?
• Pentoxifylline is a hematologic agent indicated for which condition?
• Paclitaxel acts as which type of anticancer agent?
• Pregnancy category X is associated with which anticoagulant?
• DPT vaccine provides active immunization against which diseases?
• Hydroxyzine is used for which indications?
• Bismuth subsalicylate is categorized for pregnancy as which categories?
• Methotrexate is used in the treatment of which conditions?
• Which anticonvulsant is used for seizures, trigeminal neuralgia, and prophylaxis bipolar disorder?
• Mebendazole is used to treat which type of infection?
• Which vaccine is contraindicated in pregnancy?
• Silver nitrate is used for prophylaxis in which neonatal condition?
• Bisacodyl should not be taken with what within 1 hour due to enteric coating?
• Which opioid analgesic also serves as an antitussive for mild to moderate pain?
• Which drug has a pregnancy-related caution 'do not breast feed infants <6 months'?
• Hydrocortisone is classified as which type of corticosteroid?
• Propylthiouracil is used to treat which thyroid condition?
• Estrone is indicated for which of the following?
• Which statement about atropine is true?
• Which Schedule I substance has antiemetic, analgesic, appetite stimulant, and glaucoma indications?
• Sodium phosphate enema is cautioned in which patient group?
• Amiodarone is effective in treating which types of arrhythmias?
• Donepezil is a cholinesterase inhibitor indicated for mild to moderate Alzheimer's disease. Which choice below reflects this?
• Which drug is an anti-Alzheimer's disease agent and cholinesterase inhibitor?
• Which SSRI antidepressant is used for depression, obsessive-compulsive disorder, bulimia nervosa, anorexia nervosa, fibromyalgia, panic attacks, phobias, and premenstrual dysphoric syndrome?
• Which anti-Parkinson agent is a dopamine agonist used for Parkinson's disease and restless legs syndrome, and lactation is contraindicated?
• Which statement about amlodipine is true?
• Which prostaglandin is used to prevent NSAID-induced ulcers and can terminate intrauterine pregnancy when used with methotrexate?
• Which drug is an analgesic and antitussive with Schedule II status and is used for mild to moderate pain?
• Which anticonvulsant is primarily used for epilepsy?
• Capsaicin is used for relief of pain in which condition?
• Which drug is a sedative used for disturbed biorhythms and sleep disorders?
• Which of the following is a contraindication for sumatriptan?
• Which drug has pregnancy category X?
• Which antiulcer agent forms an ulcer-adherent proteinaceous exudate complex and is used for duodenal ulcers and stress ulcers?
• Which agent has side effects of diarrhea and abdominal pain?
• Hepatitis B vaccine provides active immunization against which virus?
• HPV Quadrivalent vaccine is categorized as which type of vaccine?
• Nystatin is primarily used as which type of antifungal agent?
• Progesterone is indicated for which of the following conditions?
• Metronidazole is an antiprotozoal effective against which organisms?
• Which drug is an anxiolytic, anticonvulsant, and sedative-hypnotic used for partial seizures, emergency management of acute seizures, and preoperative sedation?
• Which drug is categorized as pregnancy category X and contraindicated in lactation?
• Medroxyprogesterone is a synthetic progestin used for which conditions?
• Phentermine is used for what purpose and what is a major contraindication?
• Cephalexin is a first-generation cephalosporin with activity against which organisms?
• Permethrin is best described as a
• Which skeletal muscle relaxant also has autonomic nervous system activity and is indicated for tetanus and painful muscle spasms?
• Donepezil is a cholinesterase inhibitor used for which condition?
• Which statement best describes spironolactone?
• Desmopressin is a synthetic analogue of vasopressin used to treat which condition?
• Which age group is a contraindication for Haemophilus influenzae type b immunization?
• Doxycycline is a tetracycline antibiotic effective against infections caused by which group of organisms?
• Penicillamine is used to chelate several metals. Which of the following metals is it known to chelate?
• Which drug is commonly associated with black hairy tongue as a side effect?
• Which analgesic/antipyretic has a maximum daily dose of 4 grams and may cause liver injury with alcohol?
• Methotrexate is best described as which type of agent?
• Doxorubicin is best described as which class of anticancer drug?
• Which statement about testosterone's biological effects is true?
• Which narcotic is Schedule I and listed with uses including treatment of acute pain, MI, acute pulmonary edema, and chronic pain?
• Which antidepressant is a monoamine oxidase inhibitor (MAOI) used for atypical depression?
• Which antispasmodic reduces GI tone and motility by blocking muscarinic receptors?
• Rotavirus vaccine is classified as which type of vaccine?
• Which drug is an antiplatelet used for prophylaxis of thromboembolic disorders and acute coronary syndrome?
• Dextroamphetamine is best described as a central nervous system stimulant indicated for which conditions?
• Sulfasalazine is indicated as a second-line anti-inflammatory agent for which conditions?
• Which drug requires the patient to remain upright for at least 30 minutes after administration?
• Which NSAID is indicated for migraine and dysmenorrhea?
• Doxorubicin is indicated for which cancers?
• Which drug has Pregnancy Category B?
• Hydroxychloroquine is used for which of the following conditions?
• Among its listed adverse effects, which is commonly associated with atorvastatin?
• Which drug has pregnancy category X?
• Which medication is described as antidepressant, smoking cessation aid, and lowers seizure threshold as a contraindication?
• Which opioid analgesic is a narcotic agonist used for analgesia?
• Celecoxib is indicated for which of the following conditions?
• In addition to metal chelation, penicillamine is used to treat which autoimmune condition?
• Isotretinoin is primarily used for which condition?
• Which NSAID is indicated for pain, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, migraine, and dysmenorrhea?
• Fluticasone is primarily used as which type of therapy?
• Which leukotriene receptor antagonist is used for chronic asthma, allergic rhinitis, and prophylaxis of exercise-induced asthma?
• Propylthiouracil is associated with which common adverse effect?
• Levonorgestrel intrauterine device is best described as which of the following?
• Which anticonvulsant is used for epilepsy and neuropathic pain?
• Which tricyclic antidepressant is indicated for mood depression and chronic pain and has special considerations avoiding MAOIs and SSRIs?
• DMSA is used as a chelation agent for which heavy metal?
• A notable side effect of phenoazopyridine is discoloration of urine. Which color change is characteristic?
• What is the pregnancy category for testosterone?
• Oxymetazoline is best described as which type of agent, and what is a common concern with frequent use?
• Digoxin is primarily used for which of the following?
• Which anti-Parkinson drug is associated with lactation contraindication and is used to treat Parkinson's disease?
• Which inhaled bronchodilator is an antimuscarinic used as maintenance therapy in COPD?
• Isotretinoin carries which pregnancy category?
• Which antibiotic is safe in pregnancy among the listed options?
• Which sedative/hypnotic has Pregnancy Category C?
• Which drug is a beta-2 adrenergic agonist indicated for acute bronchospasm?
• Levonorgestrel intrauterine device is used for which purpose?
• Which of the following is an insulin formulation?
• Phenoazopyridine is described as which type of medication?
• Penicillin is a beta-lactam antibiotic with activity primarily against which organisms?
• Atenolol is best described as which pharmacologic action?
• Which of the following is a contraindication for Celecoxib?
• Lisinopril is best described as which type of drug?
• Edetate calcium disodium is a chelating agent that enhances elimination of metals, particularly which metal?
• MDMA exerts its pharmacologic effect primarily by which mechanism?
• Which drug acts as an expectorant to help loosen mucus?
• Conjugated estrogens are described as which of the following?
• Ibuprofen is contraindicated to be combined with which drug?
• Colchicine is primarily used to treat which condition?
• Pneumococcal polyvalent vaccine is used to prevent disease caused by which organism?
• Estradiol is described in the material as belonging to which drug category or combination?
• Nitrofurantoin is best described as which type of antibacterial and for what condition is it commonly used?
• Sildenafil is a PDE5 inhibitor used to treat erectile dysfunction and what other condition?
• The triple antibiotic ointment contains which combination?
• Terbinafine is commonly used to treat which infections?
• Phenoazopyridine is primarily used as what kind of medication?
• Levothyroxine is a synthetic form of which thyroid hormone?
• Paclitaxel has which pregnancy category?
• Which atypical antipsychotic is used for schizophrenia and other psychotic disorders and has lactation contraindication?
• DMSA is used as a lead chelation agent. Which metal is targeted?
• DMPS is a chelating agent that binds several metals. Which metals is it known to chelate?
• DHEA is an anabolic steroid that can increase which hormones?
• Which anti-Parkinson agent is a dopamine agonist used for Parkinson's disease and restless legs syndrome?
• Interferon-alpha has a potentially fatal interaction due to reduced clearance of which drug?
• Cefdinir is a third-generation cephalosporin with activity against which organisms?
• Which drug is a sulfonylurea antidiabetic agent used for type 2 diabetes?
• Loperamide is best described as which type of agent?
• Which opioid is used for moderate to severe pain, cough, and analgesia during labor?
• DHEA is proposed for which condition among the following?
• Which drug is a 5-alpha reductase inhibitor used for BPH and male pattern baldness?
• Which drug is an alpha-1 blocker indicated for relief of BPH symptoms?
• Raloxifene is used for which purpose in postmenopausal women?
• Which anticonvulsant is used for epilepsy and neuropathic pain and is contraindicated in lactation?
• Which drug has Pregnancy Category B in the material?
• Sodium phosphate enema is commonly used for which purpose?
• Which benzodiazepine is long-acting?
• Amantadine is effective against which virus?
• Zidovudine is classified as which type of antiretroviral agent?
• Capsaicin reduces pain by depleting which neuropeptide from nerve endings?
• Celecoxib is best described as which type of inhibitor?
• Which adverse effect is commonly associated with clonidine?